LLM-105, a novel nitro-substituted explosive, was evaluated for its occupational toxicological characteristics. Acute oral toxicity tests showed that the maximum tolerated dose should be 8% concentration (gastric irrigation 20mL/kg) and the minimum lethal dose should be 10% (gastric irrigation 20mL/kg). Acute dermal toxicity tests showed that LD50 should be more than 2000 mg/kg. Acute eye irritation tests showed that only slight irritations were found. Skin sensitization tests showed that slight allergic reactions were found. It was suggested that LLM-105 should be generally slightly toxic under normal process which should be positive as preliminary evaluation for occupational protection.
Published in | International Journal of Ecotoxicology and Ecobiology (Volume 1, Issue 3) |
DOI | 10.11648/j.ijee.20160103.15 |
Page(s) | 88-93 |
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
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Copyright © The Author(s), 2016. Published by Science Publishing Group |
2, 6-diamino-3, 5-dinitropyrazine-l-oxide (LLM-105), Toxicological Evaluations, Occupational Toxicological Characteristics
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APA Style
Yu Weifei, Liao Longyu, Chen Feilan, He Mingzhong, Tan Dongmei, et al. (2016). Occupational Toxicological Characteristics of LLM-105 Explosives. International Journal of Ecotoxicology and Ecobiology, 1(3), 88-93. https://doi.org/10.11648/j.ijee.20160103.15
ACS Style
Yu Weifei; Liao Longyu; Chen Feilan; He Mingzhong; Tan Dongmei, et al. Occupational Toxicological Characteristics of LLM-105 Explosives. Int. J. Ecotoxicol. Ecobiol. 2016, 1(3), 88-93. doi: 10.11648/j.ijee.20160103.15
@article{10.11648/j.ijee.20160103.15, author = {Yu Weifei and Liao Longyu and Chen Feilan and He Mingzhong and Tan Dongmei and Fan Guijuan and Hao Shilong and Lu Huanchang}, title = {Occupational Toxicological Characteristics of LLM-105 Explosives}, journal = {International Journal of Ecotoxicology and Ecobiology}, volume = {1}, number = {3}, pages = {88-93}, doi = {10.11648/j.ijee.20160103.15}, url = {https://doi.org/10.11648/j.ijee.20160103.15}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijee.20160103.15}, abstract = {LLM-105, a novel nitro-substituted explosive, was evaluated for its occupational toxicological characteristics. Acute oral toxicity tests showed that the maximum tolerated dose should be 8% concentration (gastric irrigation 20mL/kg) and the minimum lethal dose should be 10% (gastric irrigation 20mL/kg). Acute dermal toxicity tests showed that LD50 should be more than 2000 mg/kg. Acute eye irritation tests showed that only slight irritations were found. Skin sensitization tests showed that slight allergic reactions were found. It was suggested that LLM-105 should be generally slightly toxic under normal process which should be positive as preliminary evaluation for occupational protection.}, year = {2016} }
TY - JOUR T1 - Occupational Toxicological Characteristics of LLM-105 Explosives AU - Yu Weifei AU - Liao Longyu AU - Chen Feilan AU - He Mingzhong AU - Tan Dongmei AU - Fan Guijuan AU - Hao Shilong AU - Lu Huanchang Y1 - 2016/10/28 PY - 2016 N1 - https://doi.org/10.11648/j.ijee.20160103.15 DO - 10.11648/j.ijee.20160103.15 T2 - International Journal of Ecotoxicology and Ecobiology JF - International Journal of Ecotoxicology and Ecobiology JO - International Journal of Ecotoxicology and Ecobiology SP - 88 EP - 93 PB - Science Publishing Group SN - 2575-1735 UR - https://doi.org/10.11648/j.ijee.20160103.15 AB - LLM-105, a novel nitro-substituted explosive, was evaluated for its occupational toxicological characteristics. Acute oral toxicity tests showed that the maximum tolerated dose should be 8% concentration (gastric irrigation 20mL/kg) and the minimum lethal dose should be 10% (gastric irrigation 20mL/kg). Acute dermal toxicity tests showed that LD50 should be more than 2000 mg/kg. Acute eye irritation tests showed that only slight irritations were found. Skin sensitization tests showed that slight allergic reactions were found. It was suggested that LLM-105 should be generally slightly toxic under normal process which should be positive as preliminary evaluation for occupational protection. VL - 1 IS - 3 ER -