Malignant Mesothelioma of Ovary is an extremely uncommon, malignant tumor of the ovary. The cause of formation of the tumor is not well understood. The clinical presentation of MMO is equivalent to Large-sizedtumors that causes cause abdominal and pelvic pain, discomfort, and weight loss. The complications of Ovarian Malignant Mesothelioma (OMM) include infertility, metastasis to various regions, and recurrence following its surgical removal. It’s prognosis is generally poor due to local invasion and metastasis of the malignancy to various body site. Here we report the case of a 50-year-old patient presenting with an increase in abdominal volume associated with a deterioration in general condition. The abdomino-pelvic CT showed a huge left ovarian without peritoneal carcinoma. The final pathologic diagnosis of ovarian malignant mesothelioma was made through histologic and immunohistochemical examination. The surgery was followed by adjuvant chemotherapy, resulting in a complete radiological response, with disease-free survival of more than one year.
Published in | World Journal of Medical Case Reports (Volume 3, Issue 1) |
DOI | 10.11648/j.wjmcr.20220301.12 |
Page(s) | 5-7 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
Copyright |
Copyright © The Author(s), 2022. Published by Science Publishing Group |
Primary Ovarian Mesothelioma, Immunohistochemistry, Incertain Prognosis
[1] | Maki Ohya, Mikiko Kobayashi, Toshiro Sozuki, Hiroyuki Kanno, Koh Nakazawa. Malignant peritoneal mesothelioma diagnosed 50 years post radiotherapy for ovarian cancer in a patient with a history of multiple malignancies: An autopsy case. Mol Clin Oncol. 2019 Oct; 11 (4): 397-400. PubMed | Google Scholar. |
[2] | Rakesh Kapoor, Philip George Kuttikat, Kim Vaiphei, Bhavana Rai, Firuza Darius Patel. A case report of peritoneal malignant mesothelioma presenting as primary ovarian mass. J Cancer Res Ther. Jul-Sep 2015; 11 (3): 654. PubMed | Google Scholar. |
[3] | Ye Rin Kim, Myung Ha Song, Jun Won Lee, Jae Ho Bae, Jong Eun Kim, Dong Muk Kang et al. Identification of tumor antigens in malignant mesothelioma. Oncol Lett. 2017 Oct; 14 (4): 4557-4562. PubMed | Google Scholar. |
[4] | Farioli A, Ottone M, Morganti AG, Compagnone G, Romani F, Cammelli S et al. Radiation-induced mesothelioma among long-term solid cancer survivors: a longitudinal analysis of SEER database. Cancer Med. 2016 May; 5 (5): 950-9. PubMed | Google Scholar. |
[5] | Boffetta P. Epidemiology of peritoneal mesothelioma: a review. Ann Oncol. 2007 Jun; 18 (6): 985-90. PubMed | Google Scholar. |
[6] | Maria Merino J. Malignant Mesothelioma Mimicking Ovarian Cancer. Int J Surg Pathol. 2010 Jun; 18 (3 Suppl): 178S-180S. PubMed | Google Scholar. |
[7] | Goldblum J, Hart WR. Localized and diffuse mesotheliomas of the genital tract and peritoneum in women. A clinicopathological study of nineteen true mesothelial neoplasms, other than adenomatoid tumors, multicystic mesotheliomas and localized fibrous tumors. Am J Surg Pathol. 1995 Oct; 19 (10): 1124-37. PubMed | Google Scholar. |
[8] | Clement PB, Young RH, Scully RE. Malignant mesotheliomas presenting as ovarian masses. A report of nine cases, including two primary ovarian mesotheliomas. Am J Surg Pathol. 1996 Sep; 20 (9): 1067-80. PubMed | Google Scholar. |
[9] | Stergios Boussiosa, Michele Moschettab, Afroditi Karathanasia, Alexandros Tsiourisc K, Foivos Kanellosc S, Konstantina Tatsid et al. Malignant peritoneal mesothelioma: clinical aspects, and therapeutic perspectives 2018. Ann Gastroenterol. 2018 Nov-Dec; 31 (6): 659-669. PubMed | Google Scholar. |
[10] | Addis BJ, Fox H. Papillary mesothelioma of ovary. Histopathology 1983; 7; 287±298. |
[11] | Husain AN, Colby TV, Ordóñez NG, Krausz T, Attanoos R, Beasley MB, Borczuk AC, Butnor K, Cagle PT, Chirieac LR, Churg A, Dacic S, Fraire A, Galateau-Salle F, Gibbs A, Gown A, Hammar S, Litzky L, Marchevsky AM, Nicholson AG, Roggli V, Travis WD, Wick M; International Mesothelioma Interest Group. Guidelines for pathologic diagnosis of malignant mesothelioma: 2012 update of the consensus statement from the International Mesothelioma Interest Group. Arch Pathol Lab Med 2013; 137: 647-67. |
[12] | Porta C, Ardizzoni A, Gaudino G, Maio M, Mutti L, Pinto C, Porru S, Puntoni R, Tassi G, Tognon M. Malignant mesothelioma in 2004: How advanced technology and new drugs are changing the perspectives of mesothelioma patients. Highlights from the VIIth Meeting of the International Mesothelioma Interest Group. Med Lav 2005; 96: 360-9. |
[13] | Ordonez NG. Role of immunohistochemistry in distinguishing epithelial peritoneal mesotheliomas from peritoneal and ovarian serous carcinomas. Am J Surg Pathol 1998; 22: 1203- 1214. |
APA Style
Adadi Hind, Fdili Alaoui Fatima-zahra, Jayi Sofia, Chaara Hekmat, Melhouf Moulay Abdelilah. (2022). Primary Ovarian Mesothelioma: About a Rare Case. World Journal of Medical Case Reports, 3(1), 5-7. https://doi.org/10.11648/j.wjmcr.20220301.12
ACS Style
Adadi Hind; Fdili Alaoui Fatima-zahra; Jayi Sofia; Chaara Hekmat; Melhouf Moulay Abdelilah. Primary Ovarian Mesothelioma: About a Rare Case. World J. Med. Case Rep. 2022, 3(1), 5-7. doi: 10.11648/j.wjmcr.20220301.12
@article{10.11648/j.wjmcr.20220301.12, author = {Adadi Hind and Fdili Alaoui Fatima-zahra and Jayi Sofia and Chaara Hekmat and Melhouf Moulay Abdelilah}, title = {Primary Ovarian Mesothelioma: About a Rare Case}, journal = {World Journal of Medical Case Reports}, volume = {3}, number = {1}, pages = {5-7}, doi = {10.11648/j.wjmcr.20220301.12}, url = {https://doi.org/10.11648/j.wjmcr.20220301.12}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.wjmcr.20220301.12}, abstract = {Malignant Mesothelioma of Ovary is an extremely uncommon, malignant tumor of the ovary. The cause of formation of the tumor is not well understood. The clinical presentation of MMO is equivalent to Large-sizedtumors that causes cause abdominal and pelvic pain, discomfort, and weight loss. The complications of Ovarian Malignant Mesothelioma (OMM) include infertility, metastasis to various regions, and recurrence following its surgical removal. It’s prognosis is generally poor due to local invasion and metastasis of the malignancy to various body site. Here we report the case of a 50-year-old patient presenting with an increase in abdominal volume associated with a deterioration in general condition. The abdomino-pelvic CT showed a huge left ovarian without peritoneal carcinoma. The final pathologic diagnosis of ovarian malignant mesothelioma was made through histologic and immunohistochemical examination. The surgery was followed by adjuvant chemotherapy, resulting in a complete radiological response, with disease-free survival of more than one year.}, year = {2022} }
TY - JOUR T1 - Primary Ovarian Mesothelioma: About a Rare Case AU - Adadi Hind AU - Fdili Alaoui Fatima-zahra AU - Jayi Sofia AU - Chaara Hekmat AU - Melhouf Moulay Abdelilah Y1 - 2022/01/20 PY - 2022 N1 - https://doi.org/10.11648/j.wjmcr.20220301.12 DO - 10.11648/j.wjmcr.20220301.12 T2 - World Journal of Medical Case Reports JF - World Journal of Medical Case Reports JO - World Journal of Medical Case Reports SP - 5 EP - 7 PB - Science Publishing Group SN - 2994-726X UR - https://doi.org/10.11648/j.wjmcr.20220301.12 AB - Malignant Mesothelioma of Ovary is an extremely uncommon, malignant tumor of the ovary. The cause of formation of the tumor is not well understood. The clinical presentation of MMO is equivalent to Large-sizedtumors that causes cause abdominal and pelvic pain, discomfort, and weight loss. The complications of Ovarian Malignant Mesothelioma (OMM) include infertility, metastasis to various regions, and recurrence following its surgical removal. It’s prognosis is generally poor due to local invasion and metastasis of the malignancy to various body site. Here we report the case of a 50-year-old patient presenting with an increase in abdominal volume associated with a deterioration in general condition. The abdomino-pelvic CT showed a huge left ovarian without peritoneal carcinoma. The final pathologic diagnosis of ovarian malignant mesothelioma was made through histologic and immunohistochemical examination. The surgery was followed by adjuvant chemotherapy, resulting in a complete radiological response, with disease-free survival of more than one year. VL - 3 IS - 1 ER -