To Evaluate the Clinical Effect of Glaucoma Drainage Valve Implantation in the Treatment of Neovascular Glaucoma - A Retrospective Study

Wang Tao; Liu Chao

doi:doi:10.11648/j.sjcm.20231204.12

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To Evaluate the Clinical Effect of Glaucoma Drainage Valve Implantation in the Treatment of Neovascular Glaucoma - A Retrospective Study

Wang Tao^*, Liu Chao

Published in Science Journal of Clinical Medicine (Volume 12, Issue 4)

Received: 15 October 2023 Accepted: 27 October 2023 Published: 9 November 2023

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Abstract

Background: Glaucoma is a group of diseases characterized by visual nipple atrophy and depression, visual field defects, vision loss and other common clinical manifestations. Neovascular glaucoma is secondary glaucoma. There are many treatment methods for neovascular glaucoma, each with its own advantages and disadvantages. There are mainly drug conservative treatment and surgical treatment. This study is a clinical feature analysis of the effect of glaucoma drain valve implantation in the treatment of neovascular glaucoma. Explain the advantages and disadvantages and research results. Research methods: The clinical data of 56 patients (56 eyes) with neovascular glaucoma who were hospitalized for glaucoma drain valve implantation from January 2022 to January 2023 were collected for retrospective analysis. The patient's follow-up time is 1 d, 1w, 1m, 3m and 1 last follow-up. The follow-up mainly includes the patient's postoperative intraocular pressure, optimal corrective vision, the number of types of anti-glaucoma drugs used and complications. The criteria for surgical success are complete success and conditional success. Comparison of intraocular pressure at different points after surgery, and the number of types of anti-glaucoma drugs used before and after surgery. Objective: To evaluate the effect of glaucoma drain valve implantation in the treatment of neovascular glaucoma. Results: The patient's preoperative intraocular pressure (39.7) mm Hg (1 mm Hg=0.133 kPa); glaucoma patients implanted 1 d, 1w, 1m, 3m and last follow-up intraocular pressure (19.5), (11.2), (12.5), (15.8) and (16.2) mm Hg after the operation with a drainage valve implantation. Compared with intraocular pressure at different points in time, the variance analysis of repeated measurements is statistically significant (F = 6.06, P<0.05).0-6 anti-glaucoma drugs were used before surgery, with an average of 5; 0-2 anti-glaucoma drugs were used after surgery, with an average of 1, and the difference before and after surgery was statistically significant (Z = 5.564, P<0.05). The complete success rate of drain valve implantation is 86.7%, and the conditional success rate is 95.3%. Postoperative complications mainly include drainage valve tube obstruction, drainage valve tube exposure, shallow anterior chamber and inclusion cystic vesicles around the drainage disk, transient superficial anterior chamber, choroid detachment. Intraocular pressure can be controlled after active symptomatic treatment of all complications.

Published in	Science Journal of Clinical Medicine (Volume 12, Issue 4)
DOI	10.11648/j.sjcm.20231204.12
Page(s)	45-48
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Drainage Implants, Glaucoma Valve, Glaucoma, Anti-Glaucoma Drugs, Angiogenesis, Glaucoma Intraocular Pressure, Eye Bleeding, Complication

References

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[3]	Wang Qi. Antiviral eye drops and traditional Chinese medicine eye smoke to treat herpes simplex viral keratitis field. Jilin Traditional Chinese Medicine, 2022, 37 (3): 260-262.
[4]	Yang Peizeng. Eye science "worms. Beijing: People's Health Publishing House, 2023: 115-116.
[5]	III Chen Ziyan, Li Qingsheng. Analysis of the clinical efficacy of traditional Chinese medicine combined with acycloguanosine in the treatment of herpes simplex virus keratitis. World Traditional Chinese Medicine, 2020, 12 (4): 825-828.
[6]	Huang Junmao, Dong Xuemei. Clinical observation field for the treatment of recurrent herpes simplex virus keratitis by nourishing qi, nourishing blood and removing wind. International Journal of Ophthalmology, 2021, 17 (12): 2318-2320.
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[8]	SIMHA A, BRAGANZA A, et a1. Anti-vascular endothelial growth factor for neovascular glaucoma [J]. The Cochrane Database of Systematic Reviews, 2023, 10 (10): CD007920.
[9]	NOOR N A, MUSTAFA S, A muscle NI W. Glaucoma drainage device implantation with adjunctive intravitreal bevacizumab in neovascular glaucoma: 3-year experience [J]. Clinical Ophthalmology (Auckland, N. Z.), 2022, 11: 1417-1422.
[10]	Mao Z, Guo X X, Zhong Y M, et a1. Surgical results of Ahmed glaucoma valve implaritation in patients with daucoma secondary to iridocorneal endothelial syndrome [J]. Eye (London, E Ngland), 2021, 35 (2): 608-615.
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[12]	ESLAMI Y, AZAPIPOUR E, MOHAMMADI M, et a1. Singe long seleral tunnel technique for prevention of Ahmed valve tube exposurem. European Journal of Ophthalmology, 2023, 29 (1): 52-56.
[13]	PAPADOPOULOS K, SCHRODER F M, SEKUNDO W. Long-term sur western cal outcomes of two different Ahmed Valve implantation techniques in refractory glauco Ma: Scleral flap VS scleral tunnel [J]. European Journal of Ophthalmology, 2022, 33 (1): 297-306.
[14]	Yang Qianjun, Hou Ping, Yao Qianhao, etc. The International Journal of Ophthalmology for Glaucoma Dedation Valve Implantation and Clinical Application. 2018, 18 (11): 2078-81.
[15]	RIVAl, ROBERTI G, ODDONE F, et a1. Ahmed glaucoma valve implant: surgical technique and complications. Clinical Ophthalmology (Auckland, N. Z.), 2022, 11: 357-367.
[16]	CH00 J Q H, CHEN Z D, KOH V, ec a1. Outcomes and complications of Ahmed tube implantation in Asian eyes [J]. Journal of Glaucoma, 2022, 27 (8): 733-738.
[17]	Deng Can, Wang Jing, Dong Kai. Clinical application of transangular scleral tunnel glaucoma drainage valve implantation in neovascular glaucoma [J]. Practical anti-blindness technology, 2023, 18 (3): 93-95, 124.

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Tao, W., Chao, L. (2023). To Evaluate the Clinical Effect of Glaucoma Drainage Valve Implantation in the Treatment of Neovascular Glaucoma - A Retrospective Study. Science Journal of Clinical Medicine, 12(4), 45-48. https://doi.org/10.11648/j.sjcm.20231204.12

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Tao, W.; Chao, L. To Evaluate the Clinical Effect of Glaucoma Drainage Valve Implantation in the Treatment of Neovascular Glaucoma - A Retrospective Study. Sci. J. Clin. Med. 2023, 12(4), 45-48. doi: 10.11648/j.sjcm.20231204.12

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AMA Style

Tao W, Chao L. To Evaluate the Clinical Effect of Glaucoma Drainage Valve Implantation in the Treatment of Neovascular Glaucoma - A Retrospective Study. Sci J Clin Med. 2023;12(4):45-48. doi: 10.11648/j.sjcm.20231204.12

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@article{10.11648/j.sjcm.20231204.12,
  author = {Wang Tao and Liu Chao},
  title = {To Evaluate the Clinical Effect of Glaucoma Drainage Valve Implantation in the Treatment of Neovascular Glaucoma - A Retrospective Study},
  journal = {Science Journal of Clinical Medicine},
  volume = {12},
  number = {4},
  pages = {45-48},
  doi = {10.11648/j.sjcm.20231204.12},
  url = {https://doi.org/10.11648/j.sjcm.20231204.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjcm.20231204.12},
  abstract = {Background: Glaucoma is a group of diseases characterized by visual nipple atrophy and depression, visual field defects, vision loss and other common clinical manifestations. Neovascular glaucoma is secondary glaucoma. There are many treatment methods for neovascular glaucoma, each with its own advantages and disadvantages. There are mainly drug conservative treatment and surgical treatment. This study is a clinical feature analysis of the effect of glaucoma drain valve implantation in the treatment of neovascular glaucoma. Explain the advantages and disadvantages and research results. Research methods: The clinical data of 56 patients (56 eyes) with neovascular glaucoma who were hospitalized for glaucoma drain valve implantation from January 2022 to January 2023 were collected for retrospective analysis. The patient's follow-up time is 1 d, 1w, 1m, 3m and 1 last follow-up. The follow-up mainly includes the patient's postoperative intraocular pressure, optimal corrective vision, the number of types of anti-glaucoma drugs used and complications. The criteria for surgical success are complete success and conditional success. Comparison of intraocular pressure at different points after surgery, and the number of types of anti-glaucoma drugs used before and after surgery. Objective: To evaluate the effect of glaucoma drain valve implantation in the treatment of neovascular glaucoma. Results: The patient's preoperative intraocular pressure (39.7) mm Hg (1 mm Hg=0.133 kPa); glaucoma patients implanted 1 d, 1w, 1m, 3m and last follow-up intraocular pressure (19.5), (11.2), (12.5), (15.8) and (16.2) mm Hg after the operation with a drainage valve implantation. Compared with intraocular pressure at different points in time, the variance analysis of repeated measurements is statistically significant (F = 6.06, P<0.05).0-6 anti-glaucoma drugs were used before surgery, with an average of 5; 0-2 anti-glaucoma drugs were used after surgery, with an average of 1, and the difference before and after surgery was statistically significant (Z = 5.564, P<0.05). The complete success rate of drain valve implantation is 86.7%, and the conditional success rate is 95.3%. Postoperative complications mainly include drainage valve tube obstruction, drainage valve tube exposure, shallow anterior chamber and inclusion cystic vesicles around the drainage disk, transient superficial anterior chamber, choroid detachment. Intraocular pressure can be controlled after active symptomatic treatment of all complications.
},
 year = {2023}
}

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TY - JOUR
T1 - To Evaluate the Clinical Effect of Glaucoma Drainage Valve Implantation in the Treatment of Neovascular Glaucoma - A Retrospective Study
AU - Wang Tao
AU - Liu Chao
Y1 - 2023/11/09
PY - 2023
N1 - https://doi.org/10.11648/j.sjcm.20231204.12
DO - 10.11648/j.sjcm.20231204.12
T2 - Science Journal of Clinical Medicine
JF - Science Journal of Clinical Medicine
JO - Science Journal of Clinical Medicine
SP - 45
EP - 48
PB - Science Publishing Group
SN - 2327-2732
UR - https://doi.org/10.11648/j.sjcm.20231204.12
AB - Background: Glaucoma is a group of diseases characterized by visual nipple atrophy and depression, visual field defects, vision loss and other common clinical manifestations. Neovascular glaucoma is secondary glaucoma. There are many treatment methods for neovascular glaucoma, each with its own advantages and disadvantages. There are mainly drug conservative treatment and surgical treatment. This study is a clinical feature analysis of the effect of glaucoma drain valve implantation in the treatment of neovascular glaucoma. Explain the advantages and disadvantages and research results. Research methods: The clinical data of 56 patients (56 eyes) with neovascular glaucoma who were hospitalized for glaucoma drain valve implantation from January 2022 to January 2023 were collected for retrospective analysis. The patient's follow-up time is 1 d, 1w, 1m, 3m and 1 last follow-up. The follow-up mainly includes the patient's postoperative intraocular pressure, optimal corrective vision, the number of types of anti-glaucoma drugs used and complications. The criteria for surgical success are complete success and conditional success. Comparison of intraocular pressure at different points after surgery, and the number of types of anti-glaucoma drugs used before and after surgery. Objective: To evaluate the effect of glaucoma drain valve implantation in the treatment of neovascular glaucoma. Results: The patient's preoperative intraocular pressure (39.7) mm Hg (1 mm Hg=0.133 kPa); glaucoma patients implanted 1 d, 1w, 1m, 3m and last follow-up intraocular pressure (19.5), (11.2), (12.5), (15.8) and (16.2) mm Hg after the operation with a drainage valve implantation. Compared with intraocular pressure at different points in time, the variance analysis of repeated measurements is statistically significant (F = 6.06, P<0.05).0-6 anti-glaucoma drugs were used before surgery, with an average of 5; 0-2 anti-glaucoma drugs were used after surgery, with an average of 1, and the difference before and after surgery was statistically significant (Z = 5.564, P<0.05). The complete success rate of drain valve implantation is 86.7%, and the conditional success rate is 95.3%. Postoperative complications mainly include drainage valve tube obstruction, drainage valve tube exposure, shallow anterior chamber and inclusion cystic vesicles around the drainage disk, transient superficial anterior chamber, choroid detachment. Intraocular pressure can be controlled after active symptomatic treatment of all complications.

VL - 12
IS - 4
ER -

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Author Information

Wang Tao

Department of Ophthalmology, Ding Zhou Tian Shun Eye Hospital, Baoding, China

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Liu Chao

Department of Surgery, Clinical Medicine, University Prima Indonesia, Medan, Indonesia

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APA Style

Tao, W., Chao, L. (2023). To Evaluate the Clinical Effect of Glaucoma Drainage Valve Implantation in the Treatment of Neovascular Glaucoma - A Retrospective Study. Science Journal of Clinical Medicine, 12(4), 45-48. https://doi.org/10.11648/j.sjcm.20231204.12

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ACS Style

Tao, W.; Chao, L. To Evaluate the Clinical Effect of Glaucoma Drainage Valve Implantation in the Treatment of Neovascular Glaucoma - A Retrospective Study. Sci. J. Clin. Med. 2023, 12(4), 45-48. doi: 10.11648/j.sjcm.20231204.12

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AMA Style

Tao W, Chao L. To Evaluate the Clinical Effect of Glaucoma Drainage Valve Implantation in the Treatment of Neovascular Glaucoma - A Retrospective Study. Sci J Clin Med. 2023;12(4):45-48. doi: 10.11648/j.sjcm.20231204.12

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@article{10.11648/j.sjcm.20231204.12,
  author = {Wang Tao and Liu Chao},
  title = {To Evaluate the Clinical Effect of Glaucoma Drainage Valve Implantation in the Treatment of Neovascular Glaucoma - A Retrospective Study},
  journal = {Science Journal of Clinical Medicine},
  volume = {12},
  number = {4},
  pages = {45-48},
  doi = {10.11648/j.sjcm.20231204.12},
  url = {https://doi.org/10.11648/j.sjcm.20231204.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjcm.20231204.12},
  abstract = {Background: Glaucoma is a group of diseases characterized by visual nipple atrophy and depression, visual field defects, vision loss and other common clinical manifestations. Neovascular glaucoma is secondary glaucoma. There are many treatment methods for neovascular glaucoma, each with its own advantages and disadvantages. There are mainly drug conservative treatment and surgical treatment. This study is a clinical feature analysis of the effect of glaucoma drain valve implantation in the treatment of neovascular glaucoma. Explain the advantages and disadvantages and research results. Research methods: The clinical data of 56 patients (56 eyes) with neovascular glaucoma who were hospitalized for glaucoma drain valve implantation from January 2022 to January 2023 were collected for retrospective analysis. The patient's follow-up time is 1 d, 1w, 1m, 3m and 1 last follow-up. The follow-up mainly includes the patient's postoperative intraocular pressure, optimal corrective vision, the number of types of anti-glaucoma drugs used and complications. The criteria for surgical success are complete success and conditional success. Comparison of intraocular pressure at different points after surgery, and the number of types of anti-glaucoma drugs used before and after surgery. Objective: To evaluate the effect of glaucoma drain valve implantation in the treatment of neovascular glaucoma. Results: The patient's preoperative intraocular pressure (39.7) mm Hg (1 mm Hg=0.133 kPa); glaucoma patients implanted 1 d, 1w, 1m, 3m and last follow-up intraocular pressure (19.5), (11.2), (12.5), (15.8) and (16.2) mm Hg after the operation with a drainage valve implantation. Compared with intraocular pressure at different points in time, the variance analysis of repeated measurements is statistically significant (F = 6.06, P<0.05).0-6 anti-glaucoma drugs were used before surgery, with an average of 5; 0-2 anti-glaucoma drugs were used after surgery, with an average of 1, and the difference before and after surgery was statistically significant (Z = 5.564, P<0.05). The complete success rate of drain valve implantation is 86.7%, and the conditional success rate is 95.3%. Postoperative complications mainly include drainage valve tube obstruction, drainage valve tube exposure, shallow anterior chamber and inclusion cystic vesicles around the drainage disk, transient superficial anterior chamber, choroid detachment. Intraocular pressure can be controlled after active symptomatic treatment of all complications.
},
 year = {2023}
}

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VL - 12
IS - 4
ER -

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