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Research Status of Three-Dimensional Pseudo-Continuous Arterial Spin Labeling in Ischemic Cerebrovascular Diseases

Received: 19 June 2018     Accepted: 1 August 2018     Published: 1 September 2018
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Abstract

Ischemic cerebrovascular disease (ICVD) is a kind of brain dysfunction caused by intracranial vascular disease, which has a serious threat to the patient's quality of life. With the development of ICVD in the direction of high incidence and young age, the early diagnosis of ICVD has become an urgent need in clinical practice. Three-dimensional pseudo-continuous arterial spin labeling (3D-pCASL) as a completely non-invasive perfusion imaging method can reflect changes of cerebral blood flow, and has been used in the study of ICVD. The aim of this paper is to review the research progress of 3D-pCASL in ICVD. By reviewing to the relevant domestic and foreign literatures on the value of ASL in ICVD in the past ten years, we found that 3D-pCASL technique has some advantages in the early evaluation of the abnormal perfusion of cerebral blood flow, the differential diagnosis, the reperfusion after cerebral infarction, the ischemic penumbra and the evaluation of prognosis, which has important guiding significance for the prevention of ICVD and the determination of the next treatment. Moreover, with the development of ASL technology and the appearance of new perfusion imaging method of ASL technology, it shows that it plays an inestimable role in the study of ischemic cerebrovascular diseases. In conclusion the role of 3D-pCASL in the cerebral perfusion of ICVD has been confirmed and has a very broad application prospect.

Published in Radiation Science and Technology (Volume 4, Issue 1)
DOI 10.11648/j.rst.20180401.11
Page(s) 1-5
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Pseudo-Continuous Arterial Spinlabeling, Ischemic Cerebrovascular Disease, Brain, Magnetic Resonance Imaging

References
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Cite This Article
  • APA Style

    Lina Zhu, Jiang Wu, Hui Zhang. (2018). Research Status of Three-Dimensional Pseudo-Continuous Arterial Spin Labeling in Ischemic Cerebrovascular Diseases. Radiation Science and Technology, 4(1), 1-5. https://doi.org/10.11648/j.rst.20180401.11

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    ACS Style

    Lina Zhu; Jiang Wu; Hui Zhang. Research Status of Three-Dimensional Pseudo-Continuous Arterial Spin Labeling in Ischemic Cerebrovascular Diseases. Radiat. Sci. Technol. 2018, 4(1), 1-5. doi: 10.11648/j.rst.20180401.11

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    AMA Style

    Lina Zhu, Jiang Wu, Hui Zhang. Research Status of Three-Dimensional Pseudo-Continuous Arterial Spin Labeling in Ischemic Cerebrovascular Diseases. Radiat Sci Technol. 2018;4(1):1-5. doi: 10.11648/j.rst.20180401.11

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  • @article{10.11648/j.rst.20180401.11,
      author = {Lina Zhu and Jiang Wu and Hui Zhang},
      title = {Research Status of Three-Dimensional Pseudo-Continuous Arterial Spin Labeling in Ischemic Cerebrovascular Diseases},
      journal = {Radiation Science and Technology},
      volume = {4},
      number = {1},
      pages = {1-5},
      doi = {10.11648/j.rst.20180401.11},
      url = {https://doi.org/10.11648/j.rst.20180401.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.rst.20180401.11},
      abstract = {Ischemic cerebrovascular disease (ICVD) is a kind of brain dysfunction caused by intracranial vascular disease, which has a serious threat to the patient's quality of life. With the development of ICVD in the direction of high incidence and young age, the early diagnosis of ICVD has become an urgent need in clinical practice. Three-dimensional pseudo-continuous arterial spin labeling (3D-pCASL) as a completely non-invasive perfusion imaging method can reflect changes of cerebral blood flow, and has been used in the study of ICVD. The aim of this paper is to review the research progress of 3D-pCASL in ICVD. By reviewing to the relevant domestic and foreign literatures on the value of ASL in ICVD in the past ten years, we found that 3D-pCASL technique has some advantages in the early evaluation of the abnormal perfusion of cerebral blood flow, the differential diagnosis, the reperfusion after cerebral infarction, the ischemic penumbra and the evaluation of prognosis, which has important guiding significance for the prevention of ICVD and the determination of the next treatment. Moreover, with the development of ASL technology and the appearance of new perfusion imaging method of ASL technology, it shows that it plays an inestimable role in the study of ischemic cerebrovascular diseases. In conclusion the role of 3D-pCASL in the cerebral perfusion of ICVD has been confirmed and has a very broad application prospect.},
     year = {2018}
    }
    

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  • TY  - JOUR
    T1  - Research Status of Three-Dimensional Pseudo-Continuous Arterial Spin Labeling in Ischemic Cerebrovascular Diseases
    AU  - Lina Zhu
    AU  - Jiang Wu
    AU  - Hui Zhang
    Y1  - 2018/09/01
    PY  - 2018
    N1  - https://doi.org/10.11648/j.rst.20180401.11
    DO  - 10.11648/j.rst.20180401.11
    T2  - Radiation Science and Technology
    JF  - Radiation Science and Technology
    JO  - Radiation Science and Technology
    SP  - 1
    EP  - 5
    PB  - Science Publishing Group
    SN  - 2575-5943
    UR  - https://doi.org/10.11648/j.rst.20180401.11
    AB  - Ischemic cerebrovascular disease (ICVD) is a kind of brain dysfunction caused by intracranial vascular disease, which has a serious threat to the patient's quality of life. With the development of ICVD in the direction of high incidence and young age, the early diagnosis of ICVD has become an urgent need in clinical practice. Three-dimensional pseudo-continuous arterial spin labeling (3D-pCASL) as a completely non-invasive perfusion imaging method can reflect changes of cerebral blood flow, and has been used in the study of ICVD. The aim of this paper is to review the research progress of 3D-pCASL in ICVD. By reviewing to the relevant domestic and foreign literatures on the value of ASL in ICVD in the past ten years, we found that 3D-pCASL technique has some advantages in the early evaluation of the abnormal perfusion of cerebral blood flow, the differential diagnosis, the reperfusion after cerebral infarction, the ischemic penumbra and the evaluation of prognosis, which has important guiding significance for the prevention of ICVD and the determination of the next treatment. Moreover, with the development of ASL technology and the appearance of new perfusion imaging method of ASL technology, it shows that it plays an inestimable role in the study of ischemic cerebrovascular diseases. In conclusion the role of 3D-pCASL in the cerebral perfusion of ICVD has been confirmed and has a very broad application prospect.
    VL  - 4
    IS  - 1
    ER  - 

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Author Information
  • Department of Magnetic Resonance, Cardiovascular Hospital of Shanxi Province, Taiyuan, China

  • Department of Magnetic Resonance, Cardiovascular Hospital of Shanxi Province, Taiyuan, China

  • Department of Magnetic Resonance, the First Hospital of Shanxi Medical University, Taiyuan, China

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