Optical Coherence Tomography as an Alternative for Diagnosing Polypoidal Choroidal Vasculopathy in Developing Countries

Armando Bautista-Barba; Erick Andres Quiroz-Gonzalez; Miguel Angel Quiroz-Reyes; Mario Leon-Meza; Alan Chew-Bonilla; Danna Alexandra Alvirde-Ayala; Federico Graue-Wiechers

doi:doi:10.11648/j.ijovs.20210604.17

Optical Coherence Tomography as an Alternative for Diagnosing Polypoidal Choroidal Vasculopathy in Developing Countries

Armando Bautista-Barba, Erick Andres Quiroz-Gonzalez, Miguel Angel Quiroz-Reyes, Mario Leon-Meza, Alan Chew-Bonilla, Danna Alexandra Alvirde-Ayala, Federico Graue-Wiechers

Published in International Journal of Ophthalmology & Visual Science (Volume 6, Issue 4)

Received: 25 October 2021 Accepted: 11 November 2021 Published: 19 November 2021

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Abstract

Introduction: Polypoidal choroidal vasculopathy (PCV) is a variant of neovascular age-related macular degeneration (nAMD). In clinical practice, PCV is frequently differentiated from nAMD or other retinal diseases using imaging modalities like optical coherence tomography, especially in ophthalmology clinics and hospitals which do not have access to indocyanine green angiography (ICGA), the gold standard in diagnosing PCV. As such, definite diagnosis of PCV is not possible in some cases and the actual prevalence of PCV remains unknown. Case series presentation: We have described a report of four patients without significant past medical history who presented with acute central or paracentral scotoma caused by PCV. Our approach to diagnosing PCV relied on the clinical manifestations of fundus fluorescein angiography (FFA) and spectral domain optical coherence tomography imaging (SS-OCT). Conclusion: In the absence of ICGA and OCT angiography in developing countries, it is essential to distinguish PCV from other retinal diseases, especially neovascular age-related macular degeneration as the treatment and prognosis of PCV differs from that of other retinal diseases. We believe that the key features observed in FFA and SS-OCT can potentially be equivalent to the findings on ICGA in accurate diagnosis of PCV, which is essential in tailoring patient treatment plans, set expectations, and find more effective and precise solutions.

Published in	International Journal of Ophthalmology & Visual Science (Volume 6, Issue 4)
DOI	10.11648/j.ijovs.20210604.17
Page(s)	219-224
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Occult Peripapillary Choroidal Neovascular Membrane, Polypoidal Choroidal Vasculopathy, Anti-VEGF, Age-Related Macular Degeneration, Type 1 Neovascularization

References

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[2]	Cheung CMG, Lai TYY, Ruamviboonsuk P, et al. Polypoidal Choroidal Vasculopathy: Definition, Pathogenesis, Diagnosis, and Management. Ophthalmology. 2018; 125 (5): 708-24. doi: 10.1016/j.ophtha.2017.11.019.
[3]	Cheung CMG, Lai TYY, Teo K, et al. Polypoidal Choroidal Vasculopathy: Consensus Nomenclature and Non-Indocyanine Green Angiography Diagnostic Criteria from the Asia-Pacific Ocular Imaging Society PCV Workgroup. Ophthalmology. 2021; 128 (3): 443-52. doi: 10.1016/j.ophtha.2020.08.006.
[4]	Lee WK, Iida T, Ogura Y, et al. Efficacy and Safety of Intravitreal Aflibercept for Polypoidal Choroidal Vasculopathy in the PLANET Study: A Randomized Clinical Trial. JAMA Ophthalmol. 2018; 136 (7): 786-93. doi: 10.1001/jamaophthalmol.2018.1804.
[5]	Chaikitmongkol V, Cheung CMG, Koizumi H, Govindahar V, Chhablani J, Lai TYY. Latest Developments in Polypoidal Choroidal Vasculopathy: Epidemiology, Etiology, Diagnosis, and Treatment. Asia-Pac J Ophthalmol. 2020; 9 (3): 260-8. doi: 10.1097/01.APO.0000656992.00746.48.
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APA Style

Armando Bautista-Barba, Erick Andres Quiroz-Gonzalez, Miguel Angel Quiroz-Reyes, Mario Leon-Meza, Alan Chew-Bonilla, et al. (2021). Optical Coherence Tomography as an Alternative for Diagnosing Polypoidal Choroidal Vasculopathy in Developing Countries. International Journal of Ophthalmology & Visual Science, 6(4), 219-224. https://doi.org/10.11648/j.ijovs.20210604.17

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ACS Style

Armando Bautista-Barba; Erick Andres Quiroz-Gonzalez; Miguel Angel Quiroz-Reyes; Mario Leon-Meza; Alan Chew-Bonilla, et al. Optical Coherence Tomography as an Alternative for Diagnosing Polypoidal Choroidal Vasculopathy in Developing Countries. Int. J. Ophthalmol. Vis. Sci. 2021, 6(4), 219-224. doi: 10.11648/j.ijovs.20210604.17

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AMA Style

Armando Bautista-Barba, Erick Andres Quiroz-Gonzalez, Miguel Angel Quiroz-Reyes, Mario Leon-Meza, Alan Chew-Bonilla, et al. Optical Coherence Tomography as an Alternative for Diagnosing Polypoidal Choroidal Vasculopathy in Developing Countries. Int J Ophthalmol Vis Sci. 2021;6(4):219-224. doi: 10.11648/j.ijovs.20210604.17

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@article{10.11648/j.ijovs.20210604.17,
  author = {Armando Bautista-Barba and Erick Andres Quiroz-Gonzalez and Miguel Angel Quiroz-Reyes and Mario Leon-Meza and Alan Chew-Bonilla and Danna Alexandra Alvirde-Ayala and Federico Graue-Wiechers},
  title = {Optical Coherence Tomography as an Alternative for Diagnosing Polypoidal Choroidal Vasculopathy in Developing Countries},
  journal = {International Journal of Ophthalmology & Visual Science},
  volume = {6},
  number = {4},
  pages = {219-224},
  doi = {10.11648/j.ijovs.20210604.17},
  url = {https://doi.org/10.11648/j.ijovs.20210604.17},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20210604.17},
  abstract = {Introduction: Polypoidal choroidal vasculopathy (PCV) is a variant of neovascular age-related macular degeneration (nAMD). In clinical practice, PCV is frequently differentiated from nAMD or other retinal diseases using imaging modalities like optical coherence tomography, especially in ophthalmology clinics and hospitals which do not have access to indocyanine green angiography (ICGA), the gold standard in diagnosing PCV. As such, definite diagnosis of PCV is not possible in some cases and the actual prevalence of PCV remains unknown. Case series presentation: We have described a report of four patients without significant past medical history who presented with acute central or paracentral scotoma caused by PCV. Our approach to diagnosing PCV relied on the clinical manifestations of fundus fluorescein angiography (FFA) and spectral domain optical coherence tomography imaging (SS-OCT). Conclusion: In the absence of ICGA and OCT angiography in developing countries, it is essential to distinguish PCV from other retinal diseases, especially neovascular age-related macular degeneration as the treatment and prognosis of PCV differs from that of other retinal diseases. We believe that the key features observed in FFA and SS-OCT can potentially be equivalent to the findings on ICGA in accurate diagnosis of PCV, which is essential in tailoring patient treatment plans, set expectations, and find more effective and precise solutions.},
 year = {2021}
}

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TY  - JOUR
T1  - Optical Coherence Tomography as an Alternative for Diagnosing Polypoidal Choroidal Vasculopathy in Developing Countries
AU  - Armando Bautista-Barba
AU  - Erick Andres Quiroz-Gonzalez
AU  - Miguel Angel Quiroz-Reyes
AU  - Mario Leon-Meza
AU  - Alan Chew-Bonilla
AU  - Danna Alexandra Alvirde-Ayala
AU  - Federico Graue-Wiechers
Y1  - 2021/11/19
PY  - 2021
N1  - https://doi.org/10.11648/j.ijovs.20210604.17
DO  - 10.11648/j.ijovs.20210604.17
T2  - International Journal of Ophthalmology & Visual Science
JF  - International Journal of Ophthalmology & Visual Science
JO  - International Journal of Ophthalmology & Visual Science
SP  - 219
EP  - 224
PB  - Science Publishing Group
SN  - 2637-3858
UR  - https://doi.org/10.11648/j.ijovs.20210604.17
AB  - Introduction: Polypoidal choroidal vasculopathy (PCV) is a variant of neovascular age-related macular degeneration (nAMD). In clinical practice, PCV is frequently differentiated from nAMD or other retinal diseases using imaging modalities like optical coherence tomography, especially in ophthalmology clinics and hospitals which do not have access to indocyanine green angiography (ICGA), the gold standard in diagnosing PCV. As such, definite diagnosis of PCV is not possible in some cases and the actual prevalence of PCV remains unknown. Case series presentation: We have described a report of four patients without significant past medical history who presented with acute central or paracentral scotoma caused by PCV. Our approach to diagnosing PCV relied on the clinical manifestations of fundus fluorescein angiography (FFA) and spectral domain optical coherence tomography imaging (SS-OCT). Conclusion: In the absence of ICGA and OCT angiography in developing countries, it is essential to distinguish PCV from other retinal diseases, especially neovascular age-related macular degeneration as the treatment and prognosis of PCV differs from that of other retinal diseases. We believe that the key features observed in FFA and SS-OCT can potentially be equivalent to the findings on ICGA in accurate diagnosis of PCV, which is essential in tailoring patient treatment plans, set expectations, and find more effective and precise solutions.
VL  - 6
IS  - 4
ER  -

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Author Information

Armando Bautista-Barba

Department of Ophthalmology, Institute of Ophthalmology, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico
Erick Andres Quiroz-Gonzalez

Department of Ophthalmology, Institute of Ophthalmology, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico
Miguel Angel Quiroz-Reyes

Retina Department, Institute of Ophthalmology, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico
Mario Leon-Meza

Department of Ophthalmology, Institute of Ophthalmology, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico
Alan Chew-Bonilla

Department of Ophthalmology, Institute of Ophthalmology, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico
Danna Alexandra Alvirde-Ayala

Department of Ophthalmology, Institute of Ophthalmology, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico
Federico Graue-Wiechers

Retina Department, Institute of Ophthalmology, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico

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APA Style

Armando Bautista-Barba, Erick Andres Quiroz-Gonzalez, Miguel Angel Quiroz-Reyes, Mario Leon-Meza, Alan Chew-Bonilla, et al. (2021). Optical Coherence Tomography as an Alternative for Diagnosing Polypoidal Choroidal Vasculopathy in Developing Countries. International Journal of Ophthalmology & Visual Science, 6(4), 219-224. https://doi.org/10.11648/j.ijovs.20210604.17

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ACS Style

Armando Bautista-Barba; Erick Andres Quiroz-Gonzalez; Miguel Angel Quiroz-Reyes; Mario Leon-Meza; Alan Chew-Bonilla, et al. Optical Coherence Tomography as an Alternative for Diagnosing Polypoidal Choroidal Vasculopathy in Developing Countries. Int. J. Ophthalmol. Vis. Sci. 2021, 6(4), 219-224. doi: 10.11648/j.ijovs.20210604.17

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AMA Style

Armando Bautista-Barba, Erick Andres Quiroz-Gonzalez, Miguel Angel Quiroz-Reyes, Mario Leon-Meza, Alan Chew-Bonilla, et al. Optical Coherence Tomography as an Alternative for Diagnosing Polypoidal Choroidal Vasculopathy in Developing Countries. Int J Ophthalmol Vis Sci. 2021;6(4):219-224. doi: 10.11648/j.ijovs.20210604.17

Copy | Download

@article{10.11648/j.ijovs.20210604.17,
  author = {Armando Bautista-Barba and Erick Andres Quiroz-Gonzalez and Miguel Angel Quiroz-Reyes and Mario Leon-Meza and Alan Chew-Bonilla and Danna Alexandra Alvirde-Ayala and Federico Graue-Wiechers},
  title = {Optical Coherence Tomography as an Alternative for Diagnosing Polypoidal Choroidal Vasculopathy in Developing Countries},
  journal = {International Journal of Ophthalmology & Visual Science},
  volume = {6},
  number = {4},
  pages = {219-224},
  doi = {10.11648/j.ijovs.20210604.17},
  url = {https://doi.org/10.11648/j.ijovs.20210604.17},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20210604.17},
  abstract = {Introduction: Polypoidal choroidal vasculopathy (PCV) is a variant of neovascular age-related macular degeneration (nAMD). In clinical practice, PCV is frequently differentiated from nAMD or other retinal diseases using imaging modalities like optical coherence tomography, especially in ophthalmology clinics and hospitals which do not have access to indocyanine green angiography (ICGA), the gold standard in diagnosing PCV. As such, definite diagnosis of PCV is not possible in some cases and the actual prevalence of PCV remains unknown. Case series presentation: We have described a report of four patients without significant past medical history who presented with acute central or paracentral scotoma caused by PCV. Our approach to diagnosing PCV relied on the clinical manifestations of fundus fluorescein angiography (FFA) and spectral domain optical coherence tomography imaging (SS-OCT). Conclusion: In the absence of ICGA and OCT angiography in developing countries, it is essential to distinguish PCV from other retinal diseases, especially neovascular age-related macular degeneration as the treatment and prognosis of PCV differs from that of other retinal diseases. We believe that the key features observed in FFA and SS-OCT can potentially be equivalent to the findings on ICGA in accurate diagnosis of PCV, which is essential in tailoring patient treatment plans, set expectations, and find more effective and precise solutions.},
 year = {2021}
}

Copy | Download

TY  - JOUR
T1  - Optical Coherence Tomography as an Alternative for Diagnosing Polypoidal Choroidal Vasculopathy in Developing Countries
AU  - Armando Bautista-Barba
AU  - Erick Andres Quiroz-Gonzalez
AU  - Miguel Angel Quiroz-Reyes
AU  - Mario Leon-Meza
AU  - Alan Chew-Bonilla
AU  - Danna Alexandra Alvirde-Ayala
AU  - Federico Graue-Wiechers
Y1  - 2021/11/19
PY  - 2021
N1  - https://doi.org/10.11648/j.ijovs.20210604.17
DO  - 10.11648/j.ijovs.20210604.17
T2  - International Journal of Ophthalmology & Visual Science
JF  - International Journal of Ophthalmology & Visual Science
JO  - International Journal of Ophthalmology & Visual Science
SP  - 219
EP  - 224
PB  - Science Publishing Group
SN  - 2637-3858
UR  - https://doi.org/10.11648/j.ijovs.20210604.17
AB  - Introduction: Polypoidal choroidal vasculopathy (PCV) is a variant of neovascular age-related macular degeneration (nAMD). In clinical practice, PCV is frequently differentiated from nAMD or other retinal diseases using imaging modalities like optical coherence tomography, especially in ophthalmology clinics and hospitals which do not have access to indocyanine green angiography (ICGA), the gold standard in diagnosing PCV. As such, definite diagnosis of PCV is not possible in some cases and the actual prevalence of PCV remains unknown. Case series presentation: We have described a report of four patients without significant past medical history who presented with acute central or paracentral scotoma caused by PCV. Our approach to diagnosing PCV relied on the clinical manifestations of fundus fluorescein angiography (FFA) and spectral domain optical coherence tomography imaging (SS-OCT). Conclusion: In the absence of ICGA and OCT angiography in developing countries, it is essential to distinguish PCV from other retinal diseases, especially neovascular age-related macular degeneration as the treatment and prognosis of PCV differs from that of other retinal diseases. We believe that the key features observed in FFA and SS-OCT can potentially be equivalent to the findings on ICGA in accurate diagnosis of PCV, which is essential in tailoring patient treatment plans, set expectations, and find more effective and precise solutions.
VL  - 6
IS  - 4
ER  -

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