Pyrano[2,3-c]pyrazole ligand and their transition metal complex with nickel (NiIIMPC) were synthesized and characterization by elemental analyses, magnetic susceptibility, FT IR, UV-Vis, and mass spectroscopy. Complex have been investigated as functional models for catechol oxidase activity by using a catechol as a model substrate. According to the kinetic measurement results, the rate of catechol oxidation follows first order kinetics. Nickel complex has been used in homogenous oxidation of catechol in presence of a green oxidant H2O2. kinetic parameters were obtained Vmax= 2.698×10-3MS-1, Km = 7.878M, kcat= 4.496×10-2S-1 and kcat/Km = 0.5707 M-1S-1.
| Published in | Biochemistry and Molecular Biology (Volume 3, Issue 1) |
| DOI | 10.11648/j.bmb.20180301.11 |
| Page(s) | 1-5 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2018. Published by Science Publishing Group |
Pyrano[2,3-c]Pyrazole, Nickel, Oxidation, Catecholase
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APA Style
Mohamed M. Al-Sayed. (2018). New Nickel Metal Complex towards Biomimetic Catecholase Enzyme Oxidation: Synthesis and Kinetics Studies. Biochemistry and Molecular Biology, 3(1), 1-5. https://doi.org/10.11648/j.bmb.20180301.11
ACS Style
Mohamed M. Al-Sayed. New Nickel Metal Complex towards Biomimetic Catecholase Enzyme Oxidation: Synthesis and Kinetics Studies. Biochem. Mol. Biol. 2018, 3(1), 1-5. doi: 10.11648/j.bmb.20180301.11
AMA Style
Mohamed M. Al-Sayed. New Nickel Metal Complex towards Biomimetic Catecholase Enzyme Oxidation: Synthesis and Kinetics Studies. Biochem Mol Biol. 2018;3(1):1-5. doi: 10.11648/j.bmb.20180301.11
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Download@article{10.11648/j.bmb.20180301.11,
author = {Mohamed M. Al-Sayed},
title = {New Nickel Metal Complex towards Biomimetic Catecholase Enzyme Oxidation: Synthesis and Kinetics Studies},
journal = {Biochemistry and Molecular Biology},
volume = {3},
number = {1},
pages = {1-5},
doi = {10.11648/j.bmb.20180301.11},
url = {https://doi.org/10.11648/j.bmb.20180301.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bmb.20180301.11},
abstract = {Pyrano[2,3-c]pyrazole ligand and their transition metal complex with nickel (NiIIMPC) were synthesized and characterization by elemental analyses, magnetic susceptibility, FT IR, UV-Vis, and mass spectroscopy. Complex have been investigated as functional models for catechol oxidase activity by using a catechol as a model substrate. According to the kinetic measurement results, the rate of catechol oxidation follows first order kinetics. Nickel complex has been used in homogenous oxidation of catechol in presence of a green oxidant H2O2. kinetic parameters were obtained Vmax= 2.698×10-3MS-1, Km = 7.878M, kcat= 4.496×10-2S-1 and kcat/Km = 0.5707 M-1S-1.},
year = {2018}
}
TY - JOUR T1 - New Nickel Metal Complex towards Biomimetic Catecholase Enzyme Oxidation: Synthesis and Kinetics Studies AU - Mohamed M. Al-Sayed Y1 - 2018/01/12 PY - 2018 N1 - https://doi.org/10.11648/j.bmb.20180301.11 DO - 10.11648/j.bmb.20180301.11 T2 - Biochemistry and Molecular Biology JF - Biochemistry and Molecular Biology JO - Biochemistry and Molecular Biology SP - 1 EP - 5 PB - Science Publishing Group SN - 2575-5048 UR - https://doi.org/10.11648/j.bmb.20180301.11 AB - Pyrano[2,3-c]pyrazole ligand and their transition metal complex with nickel (NiIIMPC) were synthesized and characterization by elemental analyses, magnetic susceptibility, FT IR, UV-Vis, and mass spectroscopy. Complex have been investigated as functional models for catechol oxidase activity by using a catechol as a model substrate. According to the kinetic measurement results, the rate of catechol oxidation follows first order kinetics. Nickel complex has been used in homogenous oxidation of catechol in presence of a green oxidant H2O2. kinetic parameters were obtained Vmax= 2.698×10-3MS-1, Km = 7.878M, kcat= 4.496×10-2S-1 and kcat/Km = 0.5707 M-1S-1. VL - 3 IS - 1 ER -
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