@article{10.11648/j.ajcem.20221004.13,
  author = {Jacob Amos Dunga and Umar Dahuwa and Yakubu Adamu and Nura Hamidu Alkali and Yusuf Bara Jibrin and Sabiu Abdu Gwalabe and Innocent Vakkai and Ballah Abubakar and Mohammad Alkali and Jafiada Jacob Musa and Umar Sabo Mustapha and Auwal Abuabakar and Yarima Yusuf Sulaiman and Sati Awang and Haruna Usman Liman and Kefas Paul Zawaya and Sule Jalva Bathnna and Sulaiman Ya’u Hamid and Shamaki Rimantso Manzo and Yunana Ezekiel Dickson and Omeh Pwaluwareino Fidelis},
  title = {RT-PCR Time to Negative Conversion Among COVID-19 Patients in State Isolation Centers North Eastern Nigeria},
  journal = {American Journal of Clinical and Experimental Medicine},
  volume = {10},
  number = {4},
  pages = {98-106},
  doi = {10.11648/j.ajcem.20221004.13},
  url = {https://doi.org/10.11648/j.ajcem.20221004.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajcem.20221004.13},
  abstract = {This study is aimed at determining the real time reverse transcriptase polymerase chain reaction (RT-PCR) time to negative conversion among COVID-19 patients in the isolation camps in northeast Nigeria. All patients who were confirmed COVID positive from February 2020 till January 2021 were considered for this study. All patients were tested using RT-PCR. COVID-19 was confirmed by detecting SARS-CoV-2 RNA in throat swab samples. A total of 319 patients that met the criteria were used for this study, data for repeat RT-PCR was obtained from the patient’s records. Of thee 319 patients there were more patients between the ages of 16-30 and 31 to 45 which represent 90 (28%) and 79 (24.8) respectively. History of recent travels within 14 days before diagnoses was the highest identifiable risk factor among the study population 169 (46.9). Symptoms of Fever 81 (19.9%), cough 77 (18.9%) and sore throat 40 (9.8%) were among the commonest presenting symptoms, while other symptoms like Sneezing, sputum, rhinorrhea, diarrhoea, Anosmia, vomiting and ageusia were also seen at varying frequencies. There were 22% of cases with co-morbidity, the most common among which were hypertension 43 (60.6%), diabetes 16 (22.5%), chronic kidney disease 4 (5.6%), heart failure 3 (4.2%), Ischemic heart disease 2 (2.8%) and chronic diseases 3 (4.2%). Within 3 weeks of isolation 86.2% of patients had negative RT-PCR repeat test and 306 (96%) had their symptoms resolved and a negative repeat RT-PCR at the end of the 6 weeks isolation period. There were 4.1% (13) mortality (p=0.001). In conclusion we found a median 2 weeks (14 days) period of negative conversion among affected patients, old age, presence of co- morbid conditions and sex are identifiable risks for delayed conversion and mortality among patients. Most patients converted within the first 3 weeks of isolation and prompt management. Therefore early presentation, prompt management and close monitoring of patients, that are aged and or with co-morbidities is paramount in reducing morbidity and mortality among SARS CoV 2 patients.},
 year = {2022}
}

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TY  - JOUR
T1  - RT-PCR Time to Negative Conversion Among COVID-19 Patients in State Isolation Centers North Eastern Nigeria
AU  - Jacob Amos Dunga
AU  - Umar Dahuwa
AU  - Yakubu Adamu
AU  - Nura Hamidu Alkali
AU  - Yusuf Bara Jibrin
AU  - Sabiu Abdu Gwalabe
AU  - Innocent Vakkai
AU  - Ballah Abubakar
AU  - Mohammad Alkali
AU  - Jafiada Jacob Musa
AU  - Umar Sabo Mustapha
AU  - Auwal Abuabakar
AU  - Yarima Yusuf Sulaiman
AU  - Sati Awang
AU  - Haruna Usman Liman
AU  - Kefas Paul Zawaya
AU  - Sule Jalva Bathnna
AU  - Sulaiman Ya’u Hamid
AU  - Shamaki Rimantso Manzo
AU  - Yunana Ezekiel Dickson
AU  - Omeh Pwaluwareino Fidelis
Y1  - 2022/08/17
PY  - 2022
N1  - https://doi.org/10.11648/j.ajcem.20221004.13
DO  - 10.11648/j.ajcem.20221004.13
T2  - American Journal of Clinical and Experimental Medicine
JF  - American Journal of Clinical and Experimental Medicine
JO  - American Journal of Clinical and Experimental Medicine
SP  - 98
EP  - 106
PB  - Science Publishing Group
SN  - 2330-8133
UR  - https://doi.org/10.11648/j.ajcem.20221004.13
AB  - This study is aimed at determining the real time reverse transcriptase polymerase chain reaction (RT-PCR) time to negative conversion among COVID-19 patients in the isolation camps in northeast Nigeria. All patients who were confirmed COVID positive from February 2020 till January 2021 were considered for this study. All patients were tested using RT-PCR. COVID-19 was confirmed by detecting SARS-CoV-2 RNA in throat swab samples. A total of 319 patients that met the criteria were used for this study, data for repeat RT-PCR was obtained from the patient’s records. Of thee 319 patients there were more patients between the ages of 16-30 and 31 to 45 which represent 90 (28%) and 79 (24.8) respectively. History of recent travels within 14 days before diagnoses was the highest identifiable risk factor among the study population 169 (46.9). Symptoms of Fever 81 (19.9%), cough 77 (18.9%) and sore throat 40 (9.8%) were among the commonest presenting symptoms, while other symptoms like Sneezing, sputum, rhinorrhea, diarrhoea, Anosmia, vomiting and ageusia were also seen at varying frequencies. There were 22% of cases with co-morbidity, the most common among which were hypertension 43 (60.6%), diabetes 16 (22.5%), chronic kidney disease 4 (5.6%), heart failure 3 (4.2%), Ischemic heart disease 2 (2.8%) and chronic diseases 3 (4.2%). Within 3 weeks of isolation 86.2% of patients had negative RT-PCR repeat test and 306 (96%) had their symptoms resolved and a negative repeat RT-PCR at the end of the 6 weeks isolation period. There were 4.1% (13) mortality (p=0.001). In conclusion we found a median 2 weeks (14 days) period of negative conversion among affected patients, old age, presence of co- morbid conditions and sex are identifiable risks for delayed conversion and mortality among patients. Most patients converted within the first 3 weeks of isolation and prompt management. Therefore early presentation, prompt management and close monitoring of patients, that are aged and or with co-morbidities is paramount in reducing morbidity and mortality among SARS CoV 2 patients.
VL  - 10
IS  - 4
ER  - 

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