Contribution to Phytotherapy Valorization of the Seed of Avocado, <i>Persea Americana</i>

Kwami Lumo Awaga; Kosi Mawuéna Novidzro; Bognam Kpensaga; Koffi Apeti Gbogbo; Et Kossi Honoré Koumaglo

doi:doi:10.11648/j.ajbls.20231105.12

| Peer-Reviewed

Contribution to Phytotherapy Valorization of the Seed of Avocado, Persea Americana

Kwami Lumo Awaga, Kosi Mawuéna Novidzro, Bognam Kpensaga, Koffi Apeti Gbogbo, Et Kossi Honoré Koumaglo

Published in American Journal of Biomedical and Life Sciences (Volume 11, Issue 5)

Received: 29 August 2023 Accepted: 13 September 2023 Published: 27 September 2023

Views: Downloads:

Download PDF

Share This Article

Twitter
Linked In
Facebook

Abstract

Plants represent an immense storehouse of biomolecules endowed with diverse biological properties. This study was carried out to analyze the phytochemical composition and evaluate the free radical scavenging and antioxidant activities of Persea americana seed. The dried avocado pit powder was first delipidated with hexane and the residue was successively extracted by maceration with ethanol-water mixture (50% -50%: v/v), and ethanol. Qualitative phytochemical analyses were carried out on the two extracts; and quantitative assays, to assess total polyphenol, flavonoid and condensed tannin contents. The free radical scavenging and antioxidant activities of the extracts were assessed. The results had revealed the presence of polyphenols, alkaloids, flavonoids, saponosides, anthocyanins, anthraquinones, steroids, cardiac glycosides, and condensed tannins in both extracts. In addition, total polyphenol, flavonoid and condensed tannin contents were: 70.427±0.113 mg GAEq/g DE and 194.986±2 mg GAEq/g DE; 19.667±1.732 mg QtEq/g DE and 23.111±0.509 mg QtEq/g DE; then 65.134±1.672 mg CEq/g DE and 203.616±4.931 mg CEq/g DE, respectively in the hydroethanolic and ethanolic extracts. The hydroethanolic extract showed a free radical scavenging activity evaluated as 13.84 ± 0.01%, whereas that of the ethanolic extract was 34.41 ± 4.70%; while measurement of antioxidant activity provided values of 24.30 ± 0.63 mg AAEq/g DE and 42.35 ± 1.20 mg AAEq /g DE, respectively. In conclusion, ethanolic extract showed better free radical scavenging and antioxidant activities, with higher contents of bioactive compounds. These results justified the common use of avocado seeds in phytotherapy in Togo for treatment of various pathologies.

Published in	American Journal of Biomedical and Life Sciences (Volume 11, Issue 5)
DOI	10.11648/j.ajbls.20231105.12
Page(s)	92-100
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Persea Americana, Seed, Phytochemical Composition, Antioxidant and Antiradical Activities

References

[1]	Medoatinsa SE, Dossa CPA, Atchade SP, Bogninou GSR, Dosseh K, Kpatcha T, Agbonon A, Ahissou H, Sohounhloue D. (2017). Antipyretic and Antianemic Activities of Three Anti-malaria Recipes from South Benin on Wistar Rats. American Journal of Pharmacological Sciences. 5 (3), 57-62. DOI: 10.12691/ajps-5-3-1.
[2]	Newman DJ, Cragg GM, Snader K. M. (2000). The influence of natural products upon drug discovery. Natural product reports. 17 (3), 215-234. doi: 10.1039/a902202c. PMID: 10888010.
[3]	Twenty-five years of research on medicinal plants in Latin America: a personal view. (2005). Journal of Ethnopharmacology. 100 (1-2): 131-134. doi: 10.1016/j.jep.2005.06.004. PMID: 16006081.
[4]	Abdelhamid IH, Hauglustaine J-M, &Abakar MT. (2016). La promotion des énergies renouvelables: Une réponse durable à la problématique énergétique des ménages ruraux au Tchad. Revue des Energies Renouvelables. 19 (1), 137-146.
[5]	Chaouche TM. (2014). Contribution à l’étude des activités biologiques des metabolites secondaires de quelques plantes médicinales, PhD Thesis, Université de Tlemcen-Abou Bekr Belkaid, Algérie.
[6]	Moreno EM. (1949). Le Coptyromimus perseae Hustache, nouvelle espèce entomologique et parasite de l’avocatier colombien. Fruits d’Outre-Mer. 4 (1), 10-15.
[7]	Batiactu. Le noyau d’avocat : Quand le pépin devient solution (de chauffage). [Updated 2016, December 14; cited 2022]. Available from: https://www.batiactu.com/edito/noyau-avocat-quand-pepin-devient-solution-chauffage-47349.php
[8]	Raymond Chia TW, Dykes GA. (2010). Antimicrobial activity of crude epicarp and seed extracts from mature avocado fruit (Persea americana) of three cultivars. Pharmaceutical Biology. 48 (7): 753-756. doi: 10.3109/13880200903273922. PMID: 20645772.
[9]	Braham C, Fraiture AL, Quatresooz P, Pierard C, Pierard G. (2002). Des" dermatomycoses banales" qui ne pardonnent pas. Revue Médicale de Liège. 57 (5), 317-319.
[10]	Ouedraogo AS, Pierre HJ, Banuls A.-L, Ouédraogo R, Godreuil S. (2017). Émergence et diffusion de la résistance aux antibiotiques en Afrique de l’Ouest : Facteurs favorisants et évaluation de la menace. Médecine et Santé Tropicales. 27 (2), 147-154.
[11]	Ogbo EM, Oyibo AE. (2008). Effects of three plant extracts (Ocimumgratissimum, Acalypha wilkesiana and Acalypha macrostachya) on post harvest pathogen of Persea americana. Journal of Medicinal Plants Research. 2 (11), 311-314.
[12]	Erdogrul ÖT. (2002). Antibacterial activities of some plant extracts used in folk medicine. Pharmaceutical Biology. 40 (4), 269-273.
[13]	Ficker CE, Arnason JT, Vindas PS, Alvarez LP, Akpagana K, Gbeassor M, De Souza C, Smith ML. (2003). Inhibition of human pathogenic fungi by ethnobotanically selected plant extracts. Mycoses. 46 (1-2), 29-37.
[14]	Maji MD, Chattopadhyay S, Kumar P, Saratchandra B. (2005). In vitro screening of some plant extracts against fungal pathogens of mulberry (Morus spp.). Archives of Phytopathology and Plant Protection. 38 (3), 157-164.
[15]	Soong Y-Y, Barlow PJ. (2004). Antioxidant activity and phenolic content of selected fruit seeds. Food chemistry. 88 (3), 411-417.
[16]	Wang W, Bostic TR, Gu L. (2010). Antioxidant capacities, procyanidins and pigments in avocados of different strains and cultivars. Food chemistry. 122 (4), 1193-1198.
[17]	Alagbaoso CA, Osakwe OS, Tokunbo II. (2017). Changes in proximate and phytochemical compositions of Persea americana mill. (avocado pear) seeds associated with ripening. Journal of Medicine and Biomedical Research. 16 (1), 28-34.
[18]	Dabas D, Ziegler GR, Lambert JD. (2019). Anti-Inflammatory Properties of a Colored Avocado Seed Extract. Adv. Food Technol. Food Technology and Nutritional Sciences Open Journal. 5 (1), 8-12. doi: 10.17140/AFTNSOJ-5-151.
[19]	Dabas D, Shegog RM, Ziegler GR, Lambert JD. (2013). Avocado (Persea americana) seed as a source of bioactive phytochemicals. Current Pharmaceutical Design. 19 (34): 6133-6140. DOI: 10.2174/1381612811319340007. PMID: 23448442.
[20]	Nga EN, Nchinda G, Mahi LL, Figuei PB, Mvondo JM, Sagnia B, Adiogo D. (2019). Phytochemical screening and evaluation of antioxidant power of hydro-ethanolic and aqueous leaves extracts of Annona muricata Linn (soursop). Health Sciences and Disease. 20 (1), 29-33.
[21]	Rajbhar K, Dawda H, Mukundan U. (2015). Polyphenols: Methods of extraction. Scientific Reviews and Chemical Communications. 5 (1), 1-6.
[22]	Daira NE-H, Maazi MC, Chefrour A. (2016). Contribution à l’étude phytochimique d’une plante médicinale (Ammoides verticillata Desf. Briq.) de l’Est Algérien. Bulletin de la Société Royale des Sciences de Liège. 85 (1), 276-290. DOI: 10.25518/0037-9565.6494.
[23]	Berrani A, Lrhorfi LA, Dahmani FZ, Fkhir H, Bengueddour R. (2015). Criblage phytochimique de deux plantes medicinales: Vitex agnus castus et Anabasis aretioïdes. ScienceLib Editions Mersenne. 7, 1-22. N°151201.
[24]	Joshi S, Prasad MS, Babu MK, Narayana SS, Satya AK. (2017). Phytochemical screening and evaluation of antioxidant, antibacterial and antifungal activity of medicinal plant Alphonsea sclerocarpa Thaw. Journal of Pharmacognosy and Phytochemistry. 6 (4), 1280-1286.
[25]	Mahmoudi S, Khali M, Mahmoudi N. (2013). Etude de l’extraction des composés phénoliques de différentes parties de la fleur d’artichaut (Cynarascolymus L.). Nature &Technology. 9, 35-40.
[26]	Kouamé TK, Siaka S, Kassi ABB, Soro Y. (2021). Détermination des teneurs en polyphénols totaux, flavonoïdes totaux et tanins de jeunes feuilles non encore ouvertes de Piliostigma thonningii (Caesalpiniaceae). International Journal of Biological and Chemical Sciences. 15 (1), 97-105.
[27]	Bouchenak O, Yagiaoui K, Benhabyles N, Laoufi R, Toubal S, El Haddad D, Oussaid S, Blizak D, Arab K. (2020). Criblage phytochimique et évaluation du pouvoir antioxydant des feuilles de Myrtus communis L. et Rhamnus alaternus L. Revue Agrobiologia. 10 (1), 1749-1761.
[28]	Adaramola B., Onigbinde A, and Shokunbi O. (2016). Physiochemical properties and antioxidant potential of Persea Americana seed oil. Chemistry International. 2 (3) 168-175.
[29]	Hamani M, Boudaoud D. (2016). Effet antifongique des extraits aqueux et éthanoliques des feuilles et des noyaux de Persea americana, Mémoire de master, Akli Mohand Oulhadj – Bouira, Algérie.
[30]	Kamagate M., Kouame NGM, Koffi E, Kadja AB, Camille K, Yao NGAR, Balayssac E, Daubrey-Potey T, N'zoue KS, Die-Kacou HM. (2016). Acute toxicity and hypoglycaemic activity of the leaf extracts of Persea americana Mill. (Lauraceae) in Wistar rats. African Journal of Pharmacy and Pharmacology. 10 (33), 690-698. https://doi.org/10.5897/AJPP2016.4617
[31]	Bourgou S, Beji RS, Medini F, Ksouri R. (2016). Effet du solvant et de la méthode d’extraction sur la teneur en composés phénoliques et les potentialités antioxydantes de Euphorbia helioscopia. Journal of New Sciences. 28 (12), 1649-1655.
[32]	Athaydes BR, Alves GM, de Assis ALEM, Gomes JVD, Rodrigues RP, Campagnaro BP, Nogueira BV, Silveira D, Kuster RM, Pereira TMC. (2019). Avocado seeds (Persea americana Mill.) prevents indomethacin-induced gastric ulcer in mice. Food Research International. 119, 751-760. DOI: 10.1016/j.foodres.2018.10.057.
[33]	Feknous S, Saidi F, Said RM. (2014). Extraction, caractérisation et identification de quelques métabolites secondaires actifs de la mélisse (Melissa officinalis L.). Nature & Technologie A- Sciences fondamentales et Engineering. 11, 07-13.
[34]	Biaye M. Actions pharmacologiques des tanins. (2002). Thèse. Université Cheick Anta Diop de Dakar, Sénégal.
[35]	Hollner, S. (2009). Développement de nouveaux traitements de protection a base d’acide carboxylique pour la conservation d’objets en fer du patrimoine culturel. PhD Thesis; Henri Poincaré University, Nancy, France.
[36]	Lubis YM, Chaidir Z, Refilda R, Dharma A. (2017). Antimicrobial activity of Persea americana peel extract from North Sumatera, Indonesia, against gram positive and gram negative bacteria in vitro. American Academic Scientific Research Journal for Engineering, Technology, and Sciences. 38 (2), 247-251.
[37]	Ferreira da Vinha A, Moreira J, Barreira S. (2013). Physicochemical parameters, phytochemical composition and antioxidant activity of the algarvian avocado (Persea americana Mill.). Journal of Agricultural Science. 5 (12), 100-109. DOI: 10.5539/jas.v5n12p100.
[38]	Segovia FJ, Hidalgo GI, Villasante J, Ramis X, Almajano MP. (2018). Avocado seed: A comparative study of antioxidant content and capacity in protecting oil models from oxidation. Molecules. 23 (10), 1-14. doi: 10.3390/molecules23102421.
[39]	Rodríguez-Carpena J-G, Morcuende D, Andrade M.-J, Kylli P, Estévez M. (2011). Phenolics, in vitro antioxidant and antimicrobial activities, and inhibition of lipid and protein oxidation in porcine patties. Journal of agricultural and food chemistry. 59 (10), 5625-5635. https://doi.org/10.1021/jf1048832
[40]	Flores M, Ortiz-Viedma J, Curaqueo A, Rodriguez A, Dovale-Rosabal G, Magaña F, Vega C, Toro M, López L, Ferreyra R. (2019). Preliminary studies of chemical and physical properties of two varieties of avocado seeds grown in Chile. Journal of Food Quality. Volume 2019, Article ID 3563750, 11 pages. https://doi.org/10.1155/2019/3563750

Cite This Article

Plain Text BibTeX RIS

APA Style

Kwami Lumo Awaga, Kosi Mawuéna Novidzro, Bognam Kpensaga, Koffi Apeti Gbogbo, Et Kossi Honoré Koumaglo. (2023). Contribution to Phytotherapy Valorization of the Seed of Avocado, Persea Americana. American Journal of Biomedical and Life Sciences, 11(5), 92-100. https://doi.org/10.11648/j.ajbls.20231105.12

Copy | Download

ACS Style

Kwami Lumo Awaga; Kosi Mawuéna Novidzro; Bognam Kpensaga; Koffi Apeti Gbogbo; Et Kossi Honoré Koumaglo. Contribution to Phytotherapy Valorization of the Seed of Avocado, Persea Americana. Am. J. Biomed. Life Sci. 2023, 11(5), 92-100. doi: 10.11648/j.ajbls.20231105.12

Copy | Download

AMA Style

Kwami Lumo Awaga, Kosi Mawuéna Novidzro, Bognam Kpensaga, Koffi Apeti Gbogbo, Et Kossi Honoré Koumaglo. Contribution to Phytotherapy Valorization of the Seed of Avocado, Persea Americana. Am J Biomed Life Sci. 2023;11(5):92-100. doi: 10.11648/j.ajbls.20231105.12

Copy | Download

@article{10.11648/j.ajbls.20231105.12,
  author = {Kwami Lumo Awaga and Kosi Mawuéna Novidzro and Bognam Kpensaga and Koffi Apeti Gbogbo and Et Kossi Honoré Koumaglo},
  title = {Contribution to Phytotherapy Valorization of the Seed of Avocado, Persea Americana},
  journal = {American Journal of Biomedical and Life Sciences},
  volume = {11},
  number = {5},
  pages = {92-100},
  doi = {10.11648/j.ajbls.20231105.12},
  url = {https://doi.org/10.11648/j.ajbls.20231105.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20231105.12},
  abstract = {Plants represent an immense storehouse of biomolecules endowed with diverse biological properties. This study was carried out to analyze the phytochemical composition and evaluate the free radical scavenging and antioxidant activities of Persea americana seed. The dried avocado pit powder was first delipidated with hexane and the residue was successively extracted by maceration with ethanol-water mixture (50% -50%: v/v), and ethanol. Qualitative phytochemical analyses were carried out on the two extracts; and quantitative assays, to assess total polyphenol, flavonoid and condensed tannin contents. The free radical scavenging and antioxidant activities of the extracts were assessed. The results had revealed the presence of polyphenols, alkaloids, flavonoids, saponosides, anthocyanins, anthraquinones, steroids, cardiac glycosides, and condensed tannins in both extracts. In addition, total polyphenol, flavonoid and condensed tannin contents were: 70.427±0.113 mg GAEq/g DE and 194.986±2 mg GAEq/g DE; 19.667±1.732 mg QtEq/g DE and 23.111±0.509 mg QtEq/g DE; then 65.134±1.672 mg CEq/g DE and 203.616±4.931 mg CEq/g DE, respectively in the hydroethanolic and ethanolic extracts. The hydroethanolic extract showed a free radical scavenging activity evaluated as 13.84 ± 0.01%, whereas that of the ethanolic extract was 34.41 ± 4.70%; while measurement of antioxidant activity provided values of 24.30 ± 0.63 mg AAEq/g DE and 42.35 ± 1.20 mg AAEq /g DE, respectively. In conclusion, ethanolic extract showed better free radical scavenging and antioxidant activities, with higher contents of bioactive compounds. These results justified the common use of avocado seeds in phytotherapy in Togo for treatment of various pathologies.},
 year = {2023}
}

Copy | Download

TY  - JOUR
T1  - Contribution to Phytotherapy Valorization of the Seed of Avocado, Persea Americana
AU  - Kwami Lumo Awaga
AU  - Kosi Mawuéna Novidzro
AU  - Bognam Kpensaga
AU  - Koffi Apeti Gbogbo
AU  - Et Kossi Honoré Koumaglo
Y1  - 2023/09/27
PY  - 2023
N1  - https://doi.org/10.11648/j.ajbls.20231105.12
DO  - 10.11648/j.ajbls.20231105.12
T2  - American Journal of Biomedical and Life Sciences
JF  - American Journal of Biomedical and Life Sciences
JO  - American Journal of Biomedical and Life Sciences
SP  - 92
EP  - 100
PB  - Science Publishing Group
SN  - 2330-880X
UR  - https://doi.org/10.11648/j.ajbls.20231105.12
AB  - Plants represent an immense storehouse of biomolecules endowed with diverse biological properties. This study was carried out to analyze the phytochemical composition and evaluate the free radical scavenging and antioxidant activities of Persea americana seed. The dried avocado pit powder was first delipidated with hexane and the residue was successively extracted by maceration with ethanol-water mixture (50% -50%: v/v), and ethanol. Qualitative phytochemical analyses were carried out on the two extracts; and quantitative assays, to assess total polyphenol, flavonoid and condensed tannin contents. The free radical scavenging and antioxidant activities of the extracts were assessed. The results had revealed the presence of polyphenols, alkaloids, flavonoids, saponosides, anthocyanins, anthraquinones, steroids, cardiac glycosides, and condensed tannins in both extracts. In addition, total polyphenol, flavonoid and condensed tannin contents were: 70.427±0.113 mg GAEq/g DE and 194.986±2 mg GAEq/g DE; 19.667±1.732 mg QtEq/g DE and 23.111±0.509 mg QtEq/g DE; then 65.134±1.672 mg CEq/g DE and 203.616±4.931 mg CEq/g DE, respectively in the hydroethanolic and ethanolic extracts. The hydroethanolic extract showed a free radical scavenging activity evaluated as 13.84 ± 0.01%, whereas that of the ethanolic extract was 34.41 ± 4.70%; while measurement of antioxidant activity provided values of 24.30 ± 0.63 mg AAEq/g DE and 42.35 ± 1.20 mg AAEq /g DE, respectively. In conclusion, ethanolic extract showed better free radical scavenging and antioxidant activities, with higher contents of bioactive compounds. These results justified the common use of avocado seeds in phytotherapy in Togo for treatment of various pathologies.
VL  - 11
IS  - 5
ER  -

Copy | Download

Author Information

Kwami Lumo Awaga

Laboratoire de Génie des Procédés et des Ressources Naturelles (LAGEPREN), Université de Lomé, Lomé, Togo
Kosi Mawuéna Novidzro

Laboratoire de Génie des Procédés et des Ressources Naturelles (LAGEPREN), Université de Lomé, Lomé, Togo
Bognam Kpensaga

Laboratoire de Génie des Procédés et des Ressources Naturelles (LAGEPREN), Université de Lomé, Lomé, Togo
Koffi Apeti Gbogbo

Laboratoire de Biologie et l’Ecologie Végétale (LBEV), University de Lomé, Lomé, Togo
Et Kossi Honoré Koumaglo

Laboratoire de Génie des Procédés et des Ressources Naturelles (LAGEPREN), Université de Lomé, Lomé, Togo

Download PDF

Sections

Plain Text BibTeX RIS

APA Style

Kwami Lumo Awaga, Kosi Mawuéna Novidzro, Bognam Kpensaga, Koffi Apeti Gbogbo, Et Kossi Honoré Koumaglo. (2023). Contribution to Phytotherapy Valorization of the Seed of Avocado, Persea Americana. American Journal of Biomedical and Life Sciences, 11(5), 92-100. https://doi.org/10.11648/j.ajbls.20231105.12

Copy | Download

ACS Style

Kwami Lumo Awaga; Kosi Mawuéna Novidzro; Bognam Kpensaga; Koffi Apeti Gbogbo; Et Kossi Honoré Koumaglo. Contribution to Phytotherapy Valorization of the Seed of Avocado, Persea Americana. Am. J. Biomed. Life Sci. 2023, 11(5), 92-100. doi: 10.11648/j.ajbls.20231105.12

Copy | Download

AMA Style

Kwami Lumo Awaga, Kosi Mawuéna Novidzro, Bognam Kpensaga, Koffi Apeti Gbogbo, Et Kossi Honoré Koumaglo. Contribution to Phytotherapy Valorization of the Seed of Avocado, Persea Americana. Am J Biomed Life Sci. 2023;11(5):92-100. doi: 10.11648/j.ajbls.20231105.12

Copy | Download

@article{10.11648/j.ajbls.20231105.12,
  author = {Kwami Lumo Awaga and Kosi Mawuéna Novidzro and Bognam Kpensaga and Koffi Apeti Gbogbo and Et Kossi Honoré Koumaglo},
  title = {Contribution to Phytotherapy Valorization of the Seed of Avocado, Persea Americana},
  journal = {American Journal of Biomedical and Life Sciences},
  volume = {11},
  number = {5},
  pages = {92-100},
  doi = {10.11648/j.ajbls.20231105.12},
  url = {https://doi.org/10.11648/j.ajbls.20231105.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbls.20231105.12},
  abstract = {Plants represent an immense storehouse of biomolecules endowed with diverse biological properties. This study was carried out to analyze the phytochemical composition and evaluate the free radical scavenging and antioxidant activities of Persea americana seed. The dried avocado pit powder was first delipidated with hexane and the residue was successively extracted by maceration with ethanol-water mixture (50% -50%: v/v), and ethanol. Qualitative phytochemical analyses were carried out on the two extracts; and quantitative assays, to assess total polyphenol, flavonoid and condensed tannin contents. The free radical scavenging and antioxidant activities of the extracts were assessed. The results had revealed the presence of polyphenols, alkaloids, flavonoids, saponosides, anthocyanins, anthraquinones, steroids, cardiac glycosides, and condensed tannins in both extracts. In addition, total polyphenol, flavonoid and condensed tannin contents were: 70.427±0.113 mg GAEq/g DE and 194.986±2 mg GAEq/g DE; 19.667±1.732 mg QtEq/g DE and 23.111±0.509 mg QtEq/g DE; then 65.134±1.672 mg CEq/g DE and 203.616±4.931 mg CEq/g DE, respectively in the hydroethanolic and ethanolic extracts. The hydroethanolic extract showed a free radical scavenging activity evaluated as 13.84 ± 0.01%, whereas that of the ethanolic extract was 34.41 ± 4.70%; while measurement of antioxidant activity provided values of 24.30 ± 0.63 mg AAEq/g DE and 42.35 ± 1.20 mg AAEq /g DE, respectively. In conclusion, ethanolic extract showed better free radical scavenging and antioxidant activities, with higher contents of bioactive compounds. These results justified the common use of avocado seeds in phytotherapy in Togo for treatment of various pathologies.},
 year = {2023}
}

Copy | Download

TY  - JOUR
T1  - Contribution to Phytotherapy Valorization of the Seed of Avocado, Persea Americana
AU  - Kwami Lumo Awaga
AU  - Kosi Mawuéna Novidzro
AU  - Bognam Kpensaga
AU  - Koffi Apeti Gbogbo
AU  - Et Kossi Honoré Koumaglo
Y1  - 2023/09/27
PY  - 2023
N1  - https://doi.org/10.11648/j.ajbls.20231105.12
DO  - 10.11648/j.ajbls.20231105.12
T2  - American Journal of Biomedical and Life Sciences
JF  - American Journal of Biomedical and Life Sciences
JO  - American Journal of Biomedical and Life Sciences
SP  - 92
EP  - 100
PB  - Science Publishing Group
SN  - 2330-880X
UR  - https://doi.org/10.11648/j.ajbls.20231105.12
AB  - Plants represent an immense storehouse of biomolecules endowed with diverse biological properties. This study was carried out to analyze the phytochemical composition and evaluate the free radical scavenging and antioxidant activities of Persea americana seed. The dried avocado pit powder was first delipidated with hexane and the residue was successively extracted by maceration with ethanol-water mixture (50% -50%: v/v), and ethanol. Qualitative phytochemical analyses were carried out on the two extracts; and quantitative assays, to assess total polyphenol, flavonoid and condensed tannin contents. The free radical scavenging and antioxidant activities of the extracts were assessed. The results had revealed the presence of polyphenols, alkaloids, flavonoids, saponosides, anthocyanins, anthraquinones, steroids, cardiac glycosides, and condensed tannins in both extracts. In addition, total polyphenol, flavonoid and condensed tannin contents were: 70.427±0.113 mg GAEq/g DE and 194.986±2 mg GAEq/g DE; 19.667±1.732 mg QtEq/g DE and 23.111±0.509 mg QtEq/g DE; then 65.134±1.672 mg CEq/g DE and 203.616±4.931 mg CEq/g DE, respectively in the hydroethanolic and ethanolic extracts. The hydroethanolic extract showed a free radical scavenging activity evaluated as 13.84 ± 0.01%, whereas that of the ethanolic extract was 34.41 ± 4.70%; while measurement of antioxidant activity provided values of 24.30 ± 0.63 mg AAEq/g DE and 42.35 ± 1.20 mg AAEq /g DE, respectively. In conclusion, ethanolic extract showed better free radical scavenging and antioxidant activities, with higher contents of bioactive compounds. These results justified the common use of avocado seeds in phytotherapy in Togo for treatment of various pathologies.
VL  - 11
IS  - 5
ER  -

Copy | Download