The aim of the present study was to evaluate the effects of the aqueous extract of Tetracarpidium conophorum kernels on semen quality and oxidative stress parameters in male rats. 20 rats were randomly divided into 4 lots of 5 animals each, and lots 1 and 2 were given distilled water and the reference molecule for 28 days, while lots 3 and 4 were treated with the aqueous extract of Tetracarpidium conophorum kernels (250 and 500 mg/kg/po). The results show that administration of aqueous extract of Tetracarpidium conophorum kernels (250 and 500 mg/kg/po) to rats produced significant dose-dependent increases (p < 0.05; p < 0.01) in sperm count and motility compared with the control lot treated with distilled water. On the other hand, pH and sperm vitality showed no significant variation (p > 0.05). Administration of the aqueous extract of Tetracarpidium conophorum kernels at the doses studied resulted in no significant variation (p > 0.05) in MDA and CAT concentrations compared with distilled water. However, there was a significant increase (p < 0.05; p < 0.001) in GSH, and GPX concentrations at the respective doses of 500, 250 and 500 mg/kg of Tetracarpidium conophorum aqueous extract compared to rats given distilled water. Chemical analysis of the aqueous extract of Tetracarpidium conophorum kernels revealed the presence of polyphenols and total flavonoids with anti-free radical and antioxidant effects. These results suggest that the aqueous extract of Tetracarpidium conophorum may have spermatogenic and antioxidant potential.
| Published in | American Journal of BioScience (Volume 11, Issue 6) |
| DOI | 10.11648/j.ajbio.20231106.15 |
| Page(s) | 164-170 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Tetracarpidium conophorum, Oxidative Stress, Semen
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APA Style
Herman, A., Landry, M. M., Gallo, M. D. -. B., Stéphane, W. L. B., Moukouma, C., et al. (2023). Effects of Aqueous Extract of Tetracarpidium conophorum (Mull. Arg.) & Hutch Kernels on Semen Quality and Oxidative Stress Parameters in Male Rats. American Journal of BioScience, 11(6), 164-170. https://doi.org/10.11648/j.ajbio.20231106.15
ACS Style
Herman, A.; Landry, M. M.; Gallo, M. D. -. B.; Stéphane, W. L. B.; Moukouma, C., et al. Effects of Aqueous Extract of Tetracarpidium conophorum (Mull. Arg.) & Hutch Kernels on Semen Quality and Oxidative Stress Parameters in Male Rats. Am. J. BioScience 2023, 11(6), 164-170. doi: 10.11648/j.ajbio.20231106.15
AMA Style
Herman A, Landry MM, Gallo MD-B, Stéphane WLB, Moukouma C, et al. Effects of Aqueous Extract of Tetracarpidium conophorum (Mull. Arg.) & Hutch Kernels on Semen Quality and Oxidative Stress Parameters in Male Rats. Am J BioScience. 2023;11(6):164-170. doi: 10.11648/j.ajbio.20231106.15
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Download@article{10.11648/j.ajbio.20231106.15,
author = {Akassa Herman and Miguel Martial Landry and Mongo Dieu -Merci Bevel Gallo and Wossolo Lingomo Bertrand Stéphane and Constantin Moukouma and Osandze Rachie and Arnaud Wilfrid Etou Ossibi and Ange Antoine Abena},
title = {Effects of Aqueous Extract of Tetracarpidium conophorum (Mull. Arg.) & Hutch Kernels on Semen Quality and Oxidative Stress Parameters in Male Rats},
journal = {American Journal of BioScience},
volume = {11},
number = {6},
pages = {164-170},
doi = {10.11648/j.ajbio.20231106.15},
url = {https://doi.org/10.11648/j.ajbio.20231106.15},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbio.20231106.15},
abstract = {The aim of the present study was to evaluate the effects of the aqueous extract of Tetracarpidium conophorum kernels on semen quality and oxidative stress parameters in male rats. 20 rats were randomly divided into 4 lots of 5 animals each, and lots 1 and 2 were given distilled water and the reference molecule for 28 days, while lots 3 and 4 were treated with the aqueous extract of Tetracarpidium conophorum kernels (250 and 500 mg/kg/po). The results show that administration of aqueous extract of Tetracarpidium conophorum kernels (250 and 500 mg/kg/po) to rats produced significant dose-dependent increases (p 0.05). Administration of the aqueous extract of Tetracarpidium conophorum kernels at the doses studied resulted in no significant variation (p > 0.05) in MDA and CAT concentrations compared with distilled water. However, there was a significant increase (p Tetracarpidium conophorum aqueous extract compared to rats given distilled water. Chemical analysis of the aqueous extract of Tetracarpidium conophorum kernels revealed the presence of polyphenols and total flavonoids with anti-free radical and antioxidant effects. These results suggest that the aqueous extract of Tetracarpidium conophorum may have spermatogenic and antioxidant potential.
},
year = {2023}
}
TY - JOUR T1 - Effects of Aqueous Extract of Tetracarpidium conophorum (Mull. Arg.) & Hutch Kernels on Semen Quality and Oxidative Stress Parameters in Male Rats AU - Akassa Herman AU - Miguel Martial Landry AU - Mongo Dieu -Merci Bevel Gallo AU - Wossolo Lingomo Bertrand Stéphane AU - Constantin Moukouma AU - Osandze Rachie AU - Arnaud Wilfrid Etou Ossibi AU - Ange Antoine Abena Y1 - 2023/12/22 PY - 2023 N1 - https://doi.org/10.11648/j.ajbio.20231106.15 DO - 10.11648/j.ajbio.20231106.15 T2 - American Journal of BioScience JF - American Journal of BioScience JO - American Journal of BioScience SP - 164 EP - 170 PB - Science Publishing Group SN - 2330-0167 UR - https://doi.org/10.11648/j.ajbio.20231106.15 AB - The aim of the present study was to evaluate the effects of the aqueous extract of Tetracarpidium conophorum kernels on semen quality and oxidative stress parameters in male rats. 20 rats were randomly divided into 4 lots of 5 animals each, and lots 1 and 2 were given distilled water and the reference molecule for 28 days, while lots 3 and 4 were treated with the aqueous extract of Tetracarpidium conophorum kernels (250 and 500 mg/kg/po). The results show that administration of aqueous extract of Tetracarpidium conophorum kernels (250 and 500 mg/kg/po) to rats produced significant dose-dependent increases (p 0.05). Administration of the aqueous extract of Tetracarpidium conophorum kernels at the doses studied resulted in no significant variation (p > 0.05) in MDA and CAT concentrations compared with distilled water. However, there was a significant increase (p Tetracarpidium conophorum aqueous extract compared to rats given distilled water. Chemical analysis of the aqueous extract of Tetracarpidium conophorum kernels revealed the presence of polyphenols and total flavonoids with anti-free radical and antioxidant effects. These results suggest that the aqueous extract of Tetracarpidium conophorum may have spermatogenic and antioxidant potential. VL - 11 IS - 6 ER -
Laboratory of Biochemistry and Pharmacology, Faculty of Health Sciences, Marien Ngouabi University, Brazzaville, Republic of the Congo; Laboratory of Animal Physiology, Faculty of Science and Technology, Marien Ngouabi University, Brazzaville, Republic of the Congo
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